Weight loss treatment for where you are now
Personalized, doctor-trusted treatment plans
GLP-1s and medication kits tailored to your unique needs
Answers to questions and ongoing care, 100% online
Prescription products require an online consultation with a healthcare provider who will determine if a prescription is appropriate. FSA/HSA eligibility and coverage varies by plan provider.
Compounded semaglutide
In stock
Starting at $199/mo.* Same active ingredient as Ozempic® and Wegovy®.
Hims can help
Start the journey
No restrictive diets, no “magic” supplements, just prescription weight loss treatment designed to fit you.
Break the cycle
It’s not you, it’s biology. Our weight loss plans go deeper to address and treat the underlying factors that affect you.
Get back in the game
Keep up with your kids, friends, and family without worries.
Improve your health
If you’re at risk for certain medical conditions or concerns, healthy weight loss may help.
Trusted
medications
GLP-1s and medication kits tailored to your unique goals, so you have all the support you need to feel your best
Trusted weight loss treatment plan
Each treatment includes access to a Certificate of Analysis (COA) confirming consistency, quality, and potency.
Personalized dosage plans
Dosage plans are tailored to your specific weight loss goals and preferences.
Unlimited access to licensed providers
Ongoing care comes from an experienced Care Team and vetted providers specializing in weight loss—at no extra cost.
Fast and free shipping
Two-day*, temperature-regulated shipping helps control the medication's temperature.
What are my weight loss treatment options through Hims?
Hims offers customized weight loss plans designed to meet your unique weight loss goals. Your provider may recommend a combination of medications, such as GLP-1 injections and oral medication kits.
We also offer evidence-based content, tips and tricks, and convenient recipes that will help you achieve the results you’re looking for.
Do you prescribe GLP-1s?
Hims offers access to compounded semaglutide (compounded GLP-1) as well as name brand options like Ozempic® and Wegovy® which are all injected weekly, if prescribed by a licensed provider.
What medications do you offer?
There are plenty of brand name and generic prescription drugs that the U.S. Food and Drug Administration has approved for people struggling with high BMI (body mass index), obesity, or other weight-related health conditions. Medications such as Ozempic® (semaglutide), Wegovy® (semaglutide), Rybelsus® (semaglutide), Mounjaro® (tirzepatide), Zepbound® (tirzepatide), Saxenda® (liraglutide), IMCIVREE® (setmelanotide), Qsymia® (phentermine-topiramate), Adipex-P® (phentermine), Lomaira® (phentermine), Alli® (orlistat), Xenical® (orlistat), Contrave® (naltrexone-bupropion), as well as other medications like antidepressants prescribed off-label. Many have also had clinical trials.
Through Hims you can get access to compounded semaglutide (the same active ingredient as Ozempic® and Wegovy®).
Hims offers access to personalized prescription medication kits that can include metformin, bupropion, topiramate, vitamin B12, and naltrexone. Taken as a once-daily pill, these medications work in different ways to support your weight loss goals.
Your provider will help you find the right medication based on your custom weight loss profile.
How much does weight loss treatment cost?
Through Hims you can get GLP-1 weight loss drugs for as little as $199 a month (when you sign up for a 12-month plan which you’ll pay for upfront in full). The oral medication kits start at just $79 a month with a 5-month plan. Total pricing varies at checkout.
Medications like GLP-1s actually don’t have to cost thousands of dollars every month without the brand name markup. At Hims, we are leveraging our size and scale to ensure access to high-quality supplies of compounded GLP-1s. This keeps prices low for our customers and ensures that providers through Hims can prescribe what is truly best for you.
How do I get started with my weight loss treatment?
You’ll begin by answering questions about your medical history and weight loss goals to create a custom weight loss profile. A licensed healthcare professional will review your information—all 100% online.
If treatment is right for you, you’ll receive a message from a provider with information about your personalized plan.
For people who haven’t had success losing body weight with lifestyle changes, counting calories, or over-the-counter options like supplements, weight loss medication can be a helpful addition to a comprehensive weight loss plan.
Be sure to share any underlying health conditions, health problems, or medical conditions with your healthcare provider as you start your weight management journey such as heart disease, type 2 diabetes, high cholesterol, high blood pressure, glaucoma, pancreatitis, thyroid conditions, blood sugar issues, constipation, heart disease, recent hospitalization, or any other adverse events in your health, or if you are pregnant or breastfeeding. Only take medical advice from a licensed medical provider.
Are video visits with a doctor required?
No video visit is required; a provider will review your information 100% online. If prescribed, you’ll get unlimited online access to message your provider as needed for follow-ups, adjustments, and answers to your questions.
Is insurance required?
No, Hims does not require insurance. We have a straight-forward approach to pricing and billing, as well as affordable generic options to make taking care of yourself as simple as possible.
How can I reimburse with FSA/HSA?
You can download a receipt of your eligible expenses and submit online for reimbursement through your FSA or HSA. Head to the "orders" tab to find your receipt.
From there, you can download your receipt and follow your FSA/HSA provider's reimbursement instructions.
What is compounded semaglutide?
Working with a licensed compounding pharmacy, Hims is able to provide medications to meet our patients’ unique needs. Hims offers compounded semaglutide, a GLP-1 injection with the same active ingredient as Wegovy® and Ozempic®.
This differs from brand-name weight loss injections, which typically come in a preloaded injection pen. But don’t worry, Hims will show you exactly how to take your injection. And you’ll have access to unlimited messaging.
How much weight can I lose with weight loss medications?
As a science-backed weight loss program that’s been developed by experts, your unique treatment plan is designed to support healthy, sustainable results.
Because everyone’s weight loss journey is different, the timeline for results may vary from person to person. In general, it’s important to incorporate healthy lifestyle and wellness changes such as:
- Taking your medication as directed
- Supporting your progress with healthy nutrition
- Incorporating consistent, moderate physical activity into your routine
How is Hims dealing with GLP-1 shortages?
Through Hims, you can find GLP-1s like Ozempic® and Wegovy®—but knowing that the availability of those medications can change, Hims is working closely with trusted partners to support our customers in accessing the weight loss treatment that is right for them using pharmacy compounding.
While name-brand FDA-approved drugs like Ozempic® and Wegovy® are currently in short supply, Hims also provides compounded versions of GLP-1s formulated with the same active ingredient. The formulations of these compounded semaglutide products are held to high quality standards and developed in FDA-regulated facilities. This means you can start your weight loss journey with confidence even while other drugs may be on the FDA drug shortage list.
Compounded semaglutide, including Hims & Hers’ product, is not approved or evaluated for safety, efficacy, or quality by FDA. Wegovy® (semaglutide) and Ozempic® (semaglutide) are not compounded. Wegovy® (semaglutide) is FDA-approved for weight loss. Ozempic® (semaglutide) is FDA-approved for type 2 diabetes treatment but may be prescribed off-label for weight loss at a healthcare provider’s discretion.
Who qualifies for compounded GLP-1s at Hims?
A state-licensed provider reviews the health history, weight loss goals, and unique patient needs of every individual patient to see if they qualify before prescribing any kind of treatment.
Are GLP-1s available in all states?
Unfortunately, GLP-1s are not yet available in all 50 states; however, Hims is working to expand our offering as soon as possible.
How long do I need to stay on medication?
Medication is a long-term use weight loss treatment not meant for short-term use. When you stop taking it, the triggers that previously drove unhealthy eating behaviors may return. Always speak with a licensed medical provider before stopping treatment.
When will I see results?
Remember, results aren’t instant. Because everyone’s weight loss journey is different, the timeline for results may vary from person to person.
What is a certificate of analysis?
It’s a document that verifies a compounded GLP-1 prescription’s consistency, consistency, and potency.
How are compounded GLP-1s sourced?
The ingredients are sourced from FDA-regulated suppliers and the treatments are compounded in FDA-regulated facilities.
A few reviews from
real customers
Medical intake
Answer some questions about your health history, lifestyle, and goals, 100% online.
Provider evaluation
A medical professional will review your intake and determine what’s right for you.
Personalized plan
If prescribed, you’ll get a customized holistic plan designed to work for you.
Ongoing support
Get unlimited online access to follow-ups, adjustments, and answers to questions.
Important Safety Information
BUPROPION XL (Wellbutrin XL©) is a prescription medicine that is FDA approved to treat adults with a certain type of depression called major depressive disorder, and for the prevention of autumn-winter seasonal depression (seasonal affective disorder).
When prescribed off-label Bupropion may help some adults with overweight and obesity lose weight and keep the weight off.
Do not take Buspirone if you:
- Are allergic to Buspirone, or any of the ingredients in Buspirone
- Have severe liver or kidney problems
- Have benzodiazepine dependence
- Take any medicines for Parkinson’s Disease or depression called monoamine oxidase inhibitors (MAOI), or if you have stopped taking an MAOI in the last 14 days as they may cause a dangerous increase in blood pressure. MAOIs include, but are not limited to:
- isocarboxazid
- phenelzine
- rasagiline
- selegiline
- tranylcypromine
- Take other medication that may cause an increase in serotonin levels, such as
- linezolid
- methylene blue
- tryptophan
Before taking Buspirone, inform your healthcare provider and pharmacist about all prescription medications you are taking or plan to take, including those to treat Parkinson’s Disease or psychiatric disorders (including antidepressants or amphetamines) to avoid a potentially life-threatening condition called Serotonin Syndrome or a dangerous increase in blood pressure. Inform your healthcare provider about any over-the-counter medications, vitamins, and natural supplements, such as St. John’s Wort, that you are taking or plan to take to help avoid potentially dangerous drug-drug interactions. Be sure to mention to your prescriber if you drink grapefruit juice or eat grapefruit regularly.
Inform your healthcare provider immediately if you:
- Become severely ill and have some or all of these symptoms: agitation, hallucinations, coma, or other changes in mental status; coordination problems or muscle twitching (overactive reflexes); racing heartbeat, high or low blood pressure; sweating or fever; nausea, vomiting, or diarrhea; muscle tightness, as these may be the symptoms of a life-threatening condition called Serotonin Syndrome
- Develop restlessness or an inability to remain still, involuntary movements, hostility, or depression
- Have a rash, hives, swelling, or trouble breathing as these may be the symptoms of an allergic reaction
- Are pregnant, plan to become pregnant, or are breastfeeding
Do not stop daily Buspirone without first talking to your healthcare provider. Abruptly stopping can cause withdrawal symptoms including: vomiting, irritability, dizziness, headaches, sensation of tingling skin, or trouble sleeping.
Until you experience how this medication affects you, do not drive a car, operate potentially dangerous machinery, or perform other dangerous activities.
You should take buspirone consistently, either always with or always without food.
During your treatment with buspirone, avoid drinking large amounts of grapefruit juice.
Avoid drinking alcohol while taking Buspirone.
The most common side effects in adults treated with Buspirone include:
- Dizziness
- Drowsiness
- Diarrhea
- Nausea
- Headache
- Insomnia
- Mild congestion
- A very rare but serious side effect that may occur with buspirone therapy is serotonin syndrome. The symptoms of serotonin syndrome include, but are not limited to, a change in mental status, trouble speaking or swallowing, excessive sweating, tremors, involuntary muscle contractions, and increased body temperature. Seek emergent medical care if you are experiencing any of these symptoms as they could be a sign of a life-threatening condition.
If you miss a dose of buspirone, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and continue your regular dosing schedule. Do not double your next dose or take more than what is prescribed.
Important Safety Information
METFORMIN XR is a prescription medicine that is FDA approved to treat Type 2 diabetes mellitus when hyperglycemia cannot be managed with diet and exercise alone.
When prescribed off-label METFORMIN XR may help some adults with overweight or obesity lose weight and keep the weight off.
What is the most important information I should know about METFORMIN XR tablets?
Serious side effects can happen in people taking METFORMIN XR tablets, including:
Lactic Acidosis. Metformin, the medicine in METFORMIN XR tablets, can cause a rare, but serious, side effect called lactic acidosis (a build-up of lactic acid in the blood) that can cause death. Lactic acidosis is a medical emergency and must be treated in a hospital.Stop taking METFORMIN XR tablets and call your healthcare provider right away if you get any of the following symptoms of lactic acidosis:
- feel very weak and tired
- have unusual (not normal) muscle pain
- have trouble breathing
- have unusual sleepiness or sleep longer than usual
- have unexplained stomach or intestinal problems with nausea and vomiting, or diarrhea
- feel cold, especially in your arms and legs
- feel dizzy or lightheaded
- have a slow or irregular heartbeat
You have a higher chance of getting lactic acidosis if you:
- have kidney problems. People whose kidneys are not working properly should not take METFORMIN XR tablets.
- have liver problems.
- have congestive heart failure that requires treatment with medicines.
- drink a lot of alcohol (very often or short-term "binge" drinking).
- get dehydrated (lose a large amount of body fluids). This can happen if you are sick with a fever, vomiting, or diarrhea. Dehydration can also happen when you sweat a lot with activity or exercise and do not drink enough fluids.
- have certain x-ray tests with injectable dyes or contrast agents.
- have surgery.
- have a heart attack, severe infection, or stroke.
- are 80 years of age or older and have not had your kidney function tested.
Do not take METFORMIN XR tablets if you:
- have kidney problems
- have an abnormal creatinine level (not to exceed 500mg daily)
- are allergic to the metformin in METFORMIN XR tablets or any of the ingredients in METFORMIN XR tablets. See the medication guide for the full list of ingredients.
- are going to get an injection of dye or contrast agents for an x-ray procedure or if you are going to have surgery and not able to eat or drink much. In these situations, METFORMIN XR tablets will need to be stopped for a short time. Talk to your healthcare provider about when you should stop METFORMIN XR tablets and when you should start METFORMIN XR tablets again.
What should I tell my healthcare provider before taking METFORMIN XR tablets?
Before taking METFORMIN XR tablets, tell your healthcare provider if you:
- have type 1 diabetes. METFORMIN XR tablets should not be used to treat people with type 1 diabetes.
- have a history or risk for diabetic ketoacidosis (high levels of certain acids, known as ketones, in the blood or urine). METFORMIN XR tablets should not be used for the treatment of diabetic ketoacidosis.
- have kidney problems.
- have an abnormal creatinine level
- have liver problems.
- have heart problems, including congestive heart failure.
- are older than 80 years. If you are over 80 years old you should not take METFORMIN XR tablets unless your kidneys have been checked and they are normal.
- drink alcohol very often, or drink a lot of alcohol in short-term "binge" drinking. are taking insulin.
- have any other medical conditions.
- are pregnant or plan to become pregnant. It is not known if metformin will harm your unborn baby. If you are pregnant, talk with your healthcare provider about the best way to control your blood sugar while you are pregnant.
- are breast-feeding or plan to breast-feed. It is not known if metformin passes into your breast milk. Talk with your healthcare provider about the best way to feed your baby while you take METFORMIN XR tablets.
Tell your healthcare provider about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.
- METFORMIN XR tablets may affect the way other medicines work, and other medicines may affect how METFORMIN XR tablets work.
Common side effects of METFORMIN XR tablets include diarrhea, nausea, and upset stomach. These side effects generally go away after you take the medicine for a while. Taking your medicine with meals can help reduce these side effects. Tell your healthcare provider if the side effects bother you a lot, last for more than a few weeks, come back after they've gone away, or start later in therapy. You may need a lower dose or need to stop taking the medicine for a short period or for good.
About 3 out of every 100 people who take METFORMIN XR tablets have an unpleasant metallic taste when they start taking the medicine. It lasts for a short time.
METFORMIN XR tablets rarely cause hypoglycemia (low blood sugar) by themselves. However, hypoglycemia can happen if you do not eat enough, if you drink alcohol, or if you take other medicines to lower blood sugar.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient. The product information provided is intended only for residents of the United States. The products discussed herein may have different product labeling in different countries.
Important Safety Information
- to treat certain types of seizures (partial-onset seizures and primary generalized tonic-clonic seizures) in adults and children 2 years and older,
- with other medicines to treat certain types of seizures (partial-onset seizures, primary generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome) in adults and children 2 years and older,
- to prevent migraine headaches in adults and adolescents 12 years and older.
- Any sudden decrease in vision with or without eye pain and redness.
- A blockage of fluid in the eye causing increased pressure in the eye (secondary angle closure glaucoma).
- Feel tired
- Not feel hungry (loss of appetite)
- Feel changes in heartbeat
- Have trouble thinking clearly
| • Thoughts about suicide or dying | • Feeling agitated or restless |
| • Attempts to commit suicide | • Trouble sleeping (insomnia) |
| • New or worse depression | • New or worse irritability |
| • New or worse anxiety | • Acting aggressive, being angry or violent |
| • Panic attacks | • Acting on dangerous impulses |
| • An extreme increase in activity and talking (mania) | • Other unusual changes in behavior or mood |
- Stopping TOPIRAMATE + VITAMIN B12 suddenly can cause serious problems.
- Suicidal thoughts or actions can be caused by things other than medicines. If you have suicidal thoughts or actions, your healthcare provider may check for other causes.
- If you have epilepsy and you stop taking TOPIRAMATE + VITAMIN B12 suddenly, you may have seizures that do not stop. Your healthcare provider will tell you how to stop taking TOPIRAMATE + VITAMIN B12 slowly.
- If you miss a single dose of TOPIRAMATE + VITAMIN B12, take it as soon as you can. However, if you are within 6 hours of taking your next scheduled dose, wait until then to take your usual dose of TOPIRAMATE + VITAMIN B12 and skip the missed dose. Do not double your dose. If you have missed more than one dose, you should call your healthcare provider for advice.
- Pay attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings.
- Keep all follow-up visits with your healthcare provider as scheduled.
- Call your healthcare provider between visits as needed, especially if you are worried about symptoms.
- If you take TOPIRAMATE + VITAMIN B12 during pregnancy, your baby has a higher risk for birth defects called cleft lip and cleft palate. These defects can begin early in pregnancy, even before you know you are pregnant.
- Cleft lip and cleft palate may happen even in children born to women who are not taking any medicines and do not have other risk factors.
- There may be other medicines to treat your condition that have a lower chance of birth defects.
- All women of childbearing age should talk to their healthcare providers about using other possible treatments instead of TOPIRAMATE + VITAMIN B12. If the decision is made to use TOPIRAMATE + VITAMIN B12, you should use effective birth control (contraception) unless you are planning to become pregnant. You should talk to your doctor about the best kind of birth control to use while you are taking TOPIRAMATE + VITAMIN B12.
- Tell your healthcare provider right away if you become pregnant while taking TOPIRAMATE + VITAMIN B12. You and your healthcare provider should decide if you will continue to take TOPIRAMATE + VITAMIN B12 while you are pregnant.
- If you take TOPIRAMATE + VITAMIN B12 during pregnancy, your baby may be smaller than expected at birth. The long-term effects of this are not known. Talk to your healthcare provider if you have questions about this risk during pregnancy.
- Metabolic acidosis may have harmful effects on your baby. Talk to your healthcare provider if TOPIRAMATE + VITAMIN B12 has caused metabolic acidosis during your pregnancy.
- Pregnancy Registry: If you become pregnant while taking TOPIRAMATE + VITAMIN B12, talk to your healthcare provider about registering with the North American Antiepileptic Drug Pregnancy Registry. You can enroll in this registry by calling 1-888-233-2334. The purpose of this registry is to collect information about the safety of TOPIRAMATE + VITAMIN B12 and other antiepileptic drugs during pregnancy.
- Have or have had depression, mood problems, or suicidal thoughts or behavior
- Have kidney problems, have kidney stones, or are getting kidney dialysis
- Have a history of metabolic acidosis (too much acid in the blood)
- Have liver problems
- Have weak, brittle, or soft bones (osteomalacia, osteoporosis, osteopenia, or decreased bone density)
- Have lung or breathing problems
- Have eye problems, especially glaucoma
- Have diarrhea
- Have a growth problem
- Are on a diet high in fat and low in carbohydrates, which is called a ketogenic diet
- Are having surgery
- Are pregnant or plan to become pregnant
- Are breastfeeding or plan to breastfeed? TOPIRAMATE + VITAMIN B12 passes into breast milk. Breastfed babies may be sleepy or have diarrhea. It is not known if the TOPIRAMATE + VITAMIN B12 that passes into breast milk can cause serious harm to your baby. Talk to your healthcare provider about the best way to feed your baby if you take TOPIRAMATE + VITAMIN B12.
- Valproic acid (such as Depakene® or Depakote®).
- Any medicines that impair or decrease your thinking, concentration, or muscle coordination.
- Birth control that contains hormones (such as pills, implants, patches or injections). TOPIRAMATE + VITAMIN B12 may make your birth control less effective. Tell your healthcare provider if your menstrual bleeding changes while you are using birth control and TOPIRAMATE + VITAMIN B12.
- Take TOPIRAMATE + VITAMIN B12 exactly as prescribed.
- Your healthcare provider may change your dose. Do not change your dose without talking to your healthcare provider.
- Take TOPIRAMATE + VITAMIN B12 tablets whole. Do not chew the tablets. They may leave a bitter taste.
- TOPIRAMATE + VITAMIN B12 can be taken before, during, or after a meal. Drink plenty of fluids during the day. This may help prevent kidney stones while taking TOPIRAMATE + VITAMIN B12.
- If you take too much TOPIRAMATE + VITAMIN B12, call your healthcare provider right away or go to the nearest emergency room.
- If you miss a single dose of TOPIRAMATE + VITAMIN B12, take it as soon as you can. However, if you are within 6 hours of taking your next scheduled dose, wait until then to take your usual dose of TOPIRAMATE + VITAMIN B12 and skip the missed dose. Do not double your dose. If you have missed more than one dose, you should call your healthcare provider for advice.
- Do not stop taking TOPIRAMATE + VITAMIN B12 without talking to your healthcare provider. Stopping TOPIRAMATE + VITAMIN B12 suddenly may cause serious problems. If you have epilepsy and you stop taking TOPIRAMATE + VITAMIN B12 suddenly, you may have seizures that do not stop. Your healthcare provider will tell you how to stop taking TOPIRAMATE + VITAMIN B12 slowly.
- Your healthcare provider may do blood tests while you take TOPIRAMATE + VITAMIN B12.
- You should not drink alcohol while taking TOPIRAMATE + VITAMIN B12. TOPIRAMATE + VITAMIN B12 and alcohol can affect each other, causing side effects such as sleepiness and dizziness.
- Do not drive a car or operate machinery until you know how TOPIRAMATE + VITAMIN B12 affects you. TOPIRAMATE + VITAMIN B12 can slow your thinking and motor skills, and may affect vision.
Effects on thinking and alertness. TOPIRAMATE + VITAMIN B12 may affect how you think and cause confusion, problems with concentration, attention, memory, or speech. TOPIRAMATE + VITAMIN B12 may cause depression or mood problems, tiredness, and sleepiness.
Dizziness or loss of muscle coordination.
Serious skin reactions. TOPIRAMATE + VITAMIN B12 may cause a severe rash with blisters and peeling skin, especially around the mouth, nose, eyes, and genitals (Stevens-Johnson syndrome). TOPIRAMATE + VITAMIN B12 may also cause a rash with blisters and peeling skin over much of the body that may cause death (toxic epidermal necrolysis). Call your healthcare provider right away if you develop a skin rash or blisters.
Kidney stones. Drink plenty of fluids when taking TOPIRAMATE + VITAMIN B12 to decrease your chances of getting kidney stones.
Low body temperature. Taking TOPIRAMATE + VITAMIN B12 when you are also taking valproic acid can cause a drop in body temperature to less than 95°F, feeling tired, confusion, or coma.
| • Tingling of the arms and legs (paresthesia) | • Dizziness |
| • Not feeling hungry | • Sleepiness/drowsiness |
| • Nausea | • Slow reactions |
| • A change in the way foods taste | • Difficulty with memory |
| • Diarrhea | • Pain in the abdomen |
| • Weight loss | • Fever |
| • Nervousness | • Abnormal vision |
| • Upper respiratory tract infection | • Decreased feeling or sensitivity, especially in the skin |
| • Speech problems | |
| • Tiredness |
Important Safety Information
- Risk of opioid overdose. You can accidentally overdose in two ways.
- NALTREXONE + VITAMIN B12 blocks the effects of opioids, such as heroin or opioid pain medicines, examples include, but are not limited to; morphine (MS Contin), hydrocodone (Vicodin), oxycodone (Oxycontin), hydromorphone (Percocet), codeine, or tramadol. Do not try to overcome this blocking effect by taking large amounts of opioids—this can lead to serious injury, coma, or death.
- After you receive a dose of NALTREXONE + VITAMIN B12, its blocking effect slowly decreases and completely goes away over time. If you have used opioid street drugs or opioid-containing medicines in the past, using opioids in amounts that you used before treatment with NALTREXONE + VITAMIN B12 can lead to overdose and death. You may also be more sensitive to the effects of lower amounts of opioids:
- after you have gone through detoxification
- when your next NALTREXONE + VITAMIN B12 dose is due
- if you miss a dose of NALTREXONE + VITAMIN B12
- after you stop NALTREXONE + VITAMIN B12 treatment
- Tell your family and the people closest to you of this increased sensitivity to opioids and the risk of overdose.
- Sudden opioid withdrawal. To avoid sudden opioid withdrawal, you must stop taking any type of opioid, including street drugs; prescription pain medicines; cough, cold, or diarrhea medicines that contain opioids; or opioid-dependence treatments, including buprenorphine or methadone, for at least 7 to 14 days before starting NALTREXONE + VITAMIN B12. Sudden opioid withdrawal can be severe and may require hospitalization.
- Liver damage or hepatitis. NALTREXONE + VITAMIN B12 can cause liver damage or hepatitis. Tell your healthcare provider if you have any of these symptoms during treatment with NALTREXONE + VITAMIN B12:
- stomach area pain lasting more than a few days
- dark urine
- yellowing of the whites of your eyes
- tiredness
- Your healthcare provider may need to stop treating you with NALTREXONE + VITAMIN B12 if you get signs or symptoms of a serious liver problem.
- are using or have a physical dependence on opioid-containing medicines, such as but not limited to, morphine (MS Contin), hydrocodone (Vicodin), oxycodone (Oxycontin), hydromorphone (Percocet), codeine, or tramadol. or opioid street drugs, such as heroin.
- are having opioid withdrawal symptoms. Opioid withdrawal symptoms may happen when you have been taking opioid containing medicines or opioid street drugs regularly and then stop. Symptoms of opioid withdrawal may include: anxiety, sleeplessness, yawning, fever, sweating, teary eyes, runny nose, goosebumps, shakiness, hot or cold flushes, muscle aches, muscle twitches, restlessness, nausea and vomiting, diarrhea, or stomach cramps.
- are allergic to NALTREXONE + VITAMIN B12 or any of the inactive ingredients in NALTREXONE + VITAMIN B12. See the medication guide for the full list of ingredients.
- have liver problems, use or abuse street (illegal) drugs, have hemophilia or other bleeding problems, have kidney problems, or have any other medical conditions.
- are pregnant or plan to become pregnant. It is not known if NALTREXONE + VITAMIN B12 will harm your unborn baby. are breastfeeding. NALTREXONE + VITAMIN B12 passes into breast milk. Talk - to your healthcare provider about whether you will breastfeed or take NALTREXONE + VITAMIN B12. You should not do both.
Pneumonia. Some people receiving NALTREXONE + VITAMIN B12 treatment have had a type of pneumonia that is caused by an allergic reaction. If this happens to you, you may need to be treated in the hospital.
Serious allergic reactions. Serious allergic reactions can happen during or soon after an injection of NALTREXONE + VITAMIN B12. Tell your healthcare provider or get medical help right away if you have any of these symptoms:
- skin rash
- swelling of your face, eyes, mouth, or tongue
- trouble breathing or wheezing
- chest pain
- feeling dizzy or faint
- nausea
- sleepiness
- headache
- dizziness
- vomiting
- decreased appetite
- painful joints
- muscle cramps
- cold symptoms
- trouble sleeping
- toothache